How will your role help us transform hope into reality?

The Medical Director, Medical Affairs will be responsible for development and execution of the Ayvakit / Systemic Mastocytosis medical plan and future potential allergy/immunology launches of pipeline assets as well as subsequent lifecycle management activities. You will report to the Head of SM Medical Strategy and will play a key role in bringing a transformative therapy to patients in need. In addition, you will contribute to the growth and development of the department overall, as the position works in close collaboration with all the medical affairs functions (eg. publications, HEOR, operations, scientific communications, field medical), and our commercial and clinical development colleagues. This opportunity requires strong collaboration and communication skills within a matrixed environment as well as a commitment to "rolling up one's sleeves" to get the work done. You will be based in the home office, Cambridge, MA, and will require flexibility to travel to congresses and HCP meetings.

What will you do?

• Contribute to the development and execute a cross-functionally aligned Ayvakit medical plan, to ensure successful results.
• Establish or strengthen professional relationships with the medical and scientific community and compliantly exchange scientific knowledge with thought leaders and HCPs, including 1:1 interactions, congress engagements, and advisory boards
• Lead or support Late-Stage (phase 4) Clinical Development and data generation activities
• Be a subject matter expert, sharing knowledge and providing informed recommendations to other functions as needed. In particular, collaborate with the Clinical Development and Commercial organization to ensure external-facing materials and presentations are scientifically rigorous, compliant and clinically meaningful
• Manage, mentor and contribute to building the Medical Affairs team to meet the needs of the organization
• Work with the internal teams to develop key messages regarding disease state, MOA, target product profile, and molecular diagnostics
• Support the development and execution of a medical/scientific communication strategies including a strategic, cross-functionally aligned post-hoc analysis plan
• Contribute to the publication's plans, review and approve posters, oral presentations and manuscripts
• Assess scientific/medical and educational needs across a variety of external stakeholders and subsequently develop the strategic direction for support of ISTs and CME activities, potentially chairing relevant review committees.
• Collaborate internally with clinical and regulatory departments to support the planning, execution, and management of clinical trial activities, including ensuring that appropriate institutions and academic centers have opportunities to participate in Blueprint's clinical programs.
• Support the Field Medical Science teams globally to provide expertise, materials, and support as they engage with the broader HCP community.
• Collaborate strongly and share best practices to support medical global colleagues through Ayvakit launches

What minimum qualifications do we require?

• MD, PharmD or PhD with Hematology, Allergy/Immunology, or rare disease experience is required
• Minimum of 5 years of medical affairs within the pharmaceutical industry or a combination of industry and clinical experience; previous biotech medical affairs strategy experience desired

What additional qualifications will make you a stronger candidate?

• • Launch experience is highly relevant
  • Ability to think innovatively about medical affairs strategy and accurately anticipate future consequences and trends
  • Demonstrated ability to lead by example through a matrix and model collaborative behavior by soliciting opinions, coupled with the ability to make key decisions and be effective in getting the team behind the decisions.
  • Excellent written and verbal communication skills
  • Experience conducting formal presentations to Senior Management and external opinion leaders
  • Strong analytical skills, especially with regard to understanding and interpreting scientific and clinical research and literature, are essential.
  • Demonstrated self-starter and team player with strong interpersonal skills
  • Adept, nimble, energetic and comfortable in a fast-paced, dynamic and collaborative environment
  • Capable of taking a hands-on approach and willing to "roll up one's sleeves"
  • Commitment to our Core Values: Patients First, Thoughtfulness, Urgency, Trust, Optimism

Why Blueprint?

At Blueprint Medicines, we achieve impactful results because of our global crew of compassionate innovators - the Blue Crew. Through authentic relationships and our collective entrepreneurial spirit and action, we are each empowered to take ownership and execute with strategic prioritization. We put trust in our people to break through norms and conventions using their individual strengths and insights, which drives our success.

This is the place where the extraordinary becomes reality, and you could be part of it.

Patients are waiting. Are you ready to make the leap?

Equity, Diversity, Inclusion and Affirmative Action

At Blueprint Medicines, we foster a culture of equity, diversity and inclusion. A proud Equal Employment Opportunity and Affirmative Action employer, we consider all qualified applicants without regard to race, color, sex, gender identity or expression, sexual orientation, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, or any other characteristic protected under applicable law. We are also an E-Verify Employer. We will make reasonable accommodations, absent undue hardship, for qualified individuals with known disabilities. If you are an individual with a disability in need of an accommodation with the application or recruiting process, please reach out to TotalRewards@blueprintmedicines.com.

For more information, please see our EEO-AA Policy Statement, the EEO Know Your Rights Poster, as well as our Pay Transparency Statement.

Blueprint Medicines is a fully integrated, commercial-stage, global biopharmaceutical company that invents life-changing medicines in two core, strategic areas of allergy/inflammation and oncology/hematology. We pursue discovery, development, and commercialization of therapies that potently and selectively target known drivers of disease, with focused investment in therapeutic areas where we can leverage our core expertise and business infrastructure to bring scale to our science. We are bringing an approved medicine to people living with systemic mastocytosis (SM) in the U.S. and Europe. Additionally, we have a pipeline of research and development programs that range from early science to advanced clinical trials in mast cell-mediated diseases, including SM and chronic urticaria, breast cancer, and other solid tumors vulnerable to CDK2 inhibition.

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