Sr. Engineer / Scientist
Sanford, NC 
Posted 17 days ago
Job Description


•            The qualified candidate will join the Manufacturing Science and Technology (MSAT) organization supporting biological therapeutics and vaccines.  Within MSAT, the candidate will work in the Purification Group, which develops processes for isolation and purification of recombinant proteins, polysaccharides, bioconjugates, and other biologics.

•            Projects may include execution of processes at lab and pilot scales, process development and characterization, scale-up and tech transfer to commercial manufacturing, process simulation and modeling, process troubleshooting, new technology development and implementation.

•            The incumbent will run various recovery and purification unit operations, including preparative chromatography, Tangential Flow Filtration (TFF), and Normal Flow Filtration (NFF) at lab and pilot scales, as well as providing support for commercial scale operations as needed.

•            The scope of the project work may include tasks in any or all of the following stages: scope definition, feasibility studies, cost/benefit analyses, design, specification development, project planning, implementation, and post-implementation monitoring and follow-up.

The incumbent must be capable of providing significant contributions to cross-functional projects and may lead some teams with involvement and coaching from their supervisor



  • ?            Utilizing a high level of technical expertise, the incumbent is responsible for moderately complex projects related to the development, scale-up and/or characterization of processes, equipment, and control strategies, process optimization, qualification of alternate raw materials and components, and/or technology transfer to GMP commercial manufacturing facilities.
  • ?            The candidate must be able to execute, analyze, document, and communicate results from experimental studies conducted at lab, pilot or commercial scales. The candidate must be able to interpret data and make recommendations to optimize processes, improve yields, and enhance the smooth transition from development through to successful implementation.
  • ?            The incumbent will be responsible for troubleshooting and resolving process issues, diagnosing technical problems, and determining short and long term solutions. The incumbent will be required to work both independently and in team environments and be able to coordinate multiple technical projects simultaneously in a well-organized fashion.
  • ?            The incumbent will be expected to prepare technical reports, provide oral presentations to scientists and management, and assist in the preparation of regulatory filing documents, as required.



  • . ?          Degree in Chemical/Biochemical Engineering, Biochemistry, or other related biotechnology discipline: Ph.D. degree; M.S. degree with a minimum of 2 years of relevant experience; B.S. degree with a minimum of 4 years of relevant experience.
  • ?            Technical knowledge and skills in purification of biologics achieved through industrial or academic experience in research and development, technical operations, manufacturing, etc.
  • ?            Experience with operating, monitoring and/or control of purification processes including Chromatography, Tangential Flow Filtration (TFF), and Normal Flow Filtration (NFF).



?            Able to design and execute experimental studies, analyze data, and document/communicate results

?            Standing, walking, sitting, bending as required

?            Able to lift moderate weight



?            Occasionally work off-shift, overtime, weekends and/or holidays to meet business or customer needs.

?            Occasional domestic and/or international travel

?            Work with potentially hazardous chemicals using appropriate personal protective safety equipment in a properly controlled environment


EEO & Employment Eligibility

Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status.  Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA.   Pfizer is an E-Verify employer.


Sunshine Act

Pfizer reports payments and other transfers of value to health care providers as required by federal and state transparency laws and implementing regulations. These laws and regulations require Pfizer to provide government agencies with information such as a health care provider’s name, address and the type of payments or other value received, generally for public disclosure.  Subject to further legal review and statutory or regulatory clarification, which Pfizer intends to pursue, reimbursement of recruiting expenses for licensed physicians may constitute a reportable transfer of value under the federal transparency law commonly known as the Sunshine Act.  Therefore, if you are a licensed physician who incurs recruiting expenses as a result of interviewing with Pfizer that we pay or reimburse, your name, address and the amount of payments made currently will be reported to the government.  If you have questions regarding this matter, please do not hesitate to contact your Talent Acquisition representative.


Last Date to Apply for Job: 12 April, 2018


Job Summary
Employment Term and Type
Regular, Full Time
Required Education
Bachelor's Degree
Required Experience
4+ years
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